Trimix self-injection is an effective way to generate an erection in men with erectile dysfunction. The injection involves a small needle that is injected into the side of the penis at the 10 and 2 positions. The patient or their partner must have the manual dexterity to inject the medicine safely and effectively. The volume of medicine is small and the injections are relatively painless. the erection created is natural and typically lasts from 30 to 90 minutes. Erections lasting longer than 180 minutes or 3 hours require the use of rescue medication such as oral pseudoephedrine or injectable phenylephrine. If the erection persists longer than 3 hours despite rescue medications then it needs to be treated in the urgent care or emergency room. An erection lasting longer than three hours is called priapism. Priapism is an emergency is because blood will pool in the penis and become a clot if not treated.
The trimix medications that are used today include Prostaglandin (PGE1 or Alprostadil or Caverject), Papaverine HCL, Phentolamine (Regitine), Atropine and Forskolin. Your physician will determine the best combination of medications for your condition. In order to determine which medication will be most effective, your physician may do some in-office testing to determine the smallest dose which will still be the most effective. All of the medications mentioned above have been determined to be safe for self-injection therapy. Phentolamine and Papaverine were the first medications used for the treatment of ED but they are not yet FDA approved for ED treatment. Prostaglandin has been FDA approved for ED treatment. In some instances, the injection may cause some temporary burning sensation which most commonly occurs with the amount of Prostaglandin that is used. Some practitioners are aware of the burning associated with Prostaglandin use and will mix in some lidocaine (without epi) to help alleviate the burning sensation.
Complications with Trimix Self-Injection Therapy
As with any injection therapy, there are some risks of bleeding and bruising at the site. The likelihood of infection is also possible but rarely seen with proper technique. One of the more common side effects of self-injection therapy is the development of a prolonged erection or priapism (erection lasting longer than 3 hours). Priapism can be effectively treated with oral pseudoephedrine or phenylephrine injections. Another complication that can arise from the too frequent injection is the development of permanent scarring inside the penis. If the trimix medications are injected too frequently, then they can be irritating to the penile tissues and cause scarring. Scarring can make it difficult to generate an erection even with escalating dose of medication. Self-injection treatment should be limited to once every 4 to 7 days. In some instances, trimix is not effective because there is substantial venous leakage which prevents the generation of an effective erection. In these instances, a PRP penile injection can help to rejuvenate the vessels and improve erectile quality.
Self-injection therapy is safe and effective for men with ED issues. Self-injection therapy is less costly than surgical treatments and the injections are minimally painful. The erections generated with trimix therapy typically last from 30 to 90 minutes and allow for pleasurable sex and orgasm. A consultation is required for self-injection therapy and after proper education and training, clients are often very satisfied with the results of self-injection therapy. If trimix self-injection therapy sounds right for you, call and schedule a consultation today.